Schools, museums, libraries, community centers and other public venues in over 75 countries— last week, the entire planet was firing spikes in honor of the brain during Brain Awareness Week 2024! An annual event organized and partly funded by Dana Foundation and International Brain Research Organization (IBRO), it’s the biggest joint scientific outreach in the world whose goal is to get more people to think, talk, make, partake in experiments and get generally excited about the brain.
And just like every previous year, we were part of it too, personally or in spirit through our gear! This time around, our SpikerBoxes have conquered five countries (that we know of): from our own to Canada, the UK, Serbia and Austria.
But the Serbian high school teachers and students were in for a special treat.
“How Your Brain Works” Now Speaks Serbian Too
After Spanish and Italian editions, our book “How Your Brain Works” (MIT Press, 2022) got its first expanded edition. The good news is, there are several more experiments that we worked on with our fellows since the 2023 Summer Research Fellowship. The bad news, the book is in Serbian, so the new experiments aren’t available to our US audience for the time being! We hereby extend our gratitude to Nordeus Foundation, Center for Promotion of Science and the US Embassy in Serbia, who have made it all possible.
But the book launch, several workshops and media appearances weren’t the only way we popularized neuroscience in Serbia. We also donated neuroscience combos (the book + Neuron SpikerBox Pro + Human SpikerBoxO) to 23 schools around the country. These schools are now joining the ranks with a couple Serbian universities, two primary schools and a grammar school that have already received our gear over the past years. It will translate to thousands of students getting a chance to do hands-on neuroscience in the classroom!
Over a dozen busy bees, 5 research projects, 4 hot weeks of July, countless data, iterations and coffee cups, one book of experiments to soak it all up and present to the wider audience — and the Backyard Brains 2023 US-Serbian Summer Research Fellowship rounds off. The result will hit the shelves this fall, with the new, Serbian edition of our book “How Your Brain Works” containing brand new experiments that our team started working on.
But if you expect to see a bunch of cockroaches, worms, moths and bees and other invertebrates buzzing around Belgrade’s Center for Promotion of Science lab makerspace where we spent the month, you’re in for a surprise. This time, we ventured into two completely different, even opposite realms, hoping to eventually tie them together. One is the realm of single-celled creatures who don’t seem to be hindered or bothered by their lack of brain. The other lies behind our all-powerful brain and borders on philosophy of awareness. What is consciousness and attention? How do we think what reality is — and how do we share it with others? Finally, is there a way for these two realms to inform and complement each other?
This year’s cohort was small but diverse, composed of three undergrads who flew in from the University of Michigan and four Serbian undergrads from the Universities of Belgrade and Novi Sad. One of the greatest values was the wide variety of backgrounds that came together: from neuroscience to electrical engineering, psychology, molecular biology and computer science.
If I were to show you a photo of a Rolex watch and a face of an unknown person, you’d probably be more interested in the prestigious, shiny object than the random stranger, right? However — and this may come as a surprise — your brain is much more modest and more of a social being than you think you are! 🙂
Evidence indicates that our brain reacts differently when it sees a face from when it sees any other object. This likely has to do with the way human brains have evolved, recognizing faces as something of a greater importance than random stuff.
And so we arrive at the N170 from the title of this blog post. What exactly does it mean? It‘s a very peculiar spike in EEG recordings: one that is observed approximately 170 milliseconds after a person has been exposed to a stimulus. Multiple papers state that this N170 has a higher amplitude when the stimulus is a human face rather than anything else. And that’s exactly what I set out to prove using the Human SpikerBox and several other electronic devices.
The general idea of the experiment was to record EEG of the subject as they watch a presentation consisting of photos of human faces and wristwatches. In the presentation, photos of faces and watches flash in random order, with grey screens in between. As soon as a face or a watch pops up, the goal was to send event markers to the SpikerBox and feed them into the EEG recording.
Now that the EEG recordings got their event markers, I was able to extract some valuable data of interest — such as when exactly the spike appears and what its amplitude is. The results were close to what I’d expected, with higher amplitudes for faces, but happening a bit earlier than 170 milliseconds. This may have had to do with the delay of the sensor as it sends event markers to the Spikerbox, but we’ll come to that shortly. All of this data is so cool, but it wasn’t easy getting there. Per aspera ad astra! I came across so many problems during the project that I can hardly even recall all of them. But, oh well, that’s science – you fail 95% of times and succeed only in the remaining 5%.
Anyway, to get started, I had to make a sensor reliable and sensitive enough to detect the change in screen brightness. The goal was to have it detect 6 different levels of brightness, with as small a delay as possible. Firstly, I tried with a basic photo resistor that changes its resistance according to light and uses it in a voltage divider. However, as it turned out, it had quite a delay. So I had to switch to phototransistor after spending several days on the resistor. How does a phototransistor work? It ‘generates’ current proportional to the light intensity. Fortunately, the phototransistor was good enough so I could use it in further examinations. But why do we even need that sensor?